For a long time the people of greater Sylhet have realized the Professional education and better health care services for community development. During the British period the community leaders were striving hard to establish a medical college in Sylhet with a view to develop the existing health care system.

Accordingly then the government of Asham agreed to establish a Medical College at Sylhet and construction work of the college and the hostel building started here in 1934. But due to the influence of some evil high official adviser the project was shifted to Gouhati. Then the Asham government while under pressure announced an official gazette that a medical school would be established at Sylhet instead of college. After some time the proposed building was converted to hospital in 1936 which was later upgraded to cater for British and allied troops of the Burma front in the Second World War. In the year 1948 the hospital was further upgraded and converted into a Medical School with appropriate teaching staff and residential accommodation in order to produce Licentiate Medical Faculty doctors (LMF).

Later on in 1962 then the Pakistan government, while under pressure, decided to start a five years graduate course of study leading to award the MBBS degree. The seat capacity was inadequate in relation to population.